Microbial DNA globular liquid crystal like deposits inside Lewy bodies in four Lewy dementia patients
Author(s):
Alan B MacDonald
Four autopsy brains demonstrated concurrent evidence of Diffuse Cortical Lewy Body Dementia and active Lyme neuroborreliosis in adjacent brain sites. Lewy bodies In DCLBD contain microbial DNA. Alpha Synuclein proteins, which intrinsically bind to human nuclear DNA also bind to microbial DNa deposits inside Lewy bodies in the cytoplasmic compartment of diseased neurons. This is the first report of an association between spirochetal brain infection and Lewy Body Dementia.